The Covid-19 pandemic has provoked both in Italy and in Germany wide debates among scientists, scholars of multiple disciplines and public opinion. Of course, politics has played a fundamental role in the management of the health emergency: in Italy, “collective” health has been protected through the adoption of a very wide range of regulatory acts of different nature, not always suitable to guarantee a unitary protection. In Germany, the emergency crisis has been (more) successfully managed, with the sole exception of some problems that have emerged in the coordination between the Bund and Länder in the fight against the virus. This work will analyse, from a comparative point of view, the relationship between the legislative power and science in defining policies to combat the health emergency, focusing on the impact of such policies on the academic context.